The Osteosarcoma Collaborative

Educate • Fund Research • Cure

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“It’s Osteosarcoma” are words no one is prepared to hear. After learning more about the cancer itself, the next thing most patients and families do is ask about treatment. At that point they are stunned to learn that the standard of care for newly diagnosed Osteosarcoma has not changed in over 35 years! We must change that. Osteosarcoma, we are coming for you!

Clinical Information & Resources


In the United States, current treatment for osteosarcoma typically follows a treatment protocol referred to as the “MAP” protocol: M = Methotrexate, A = Adriamycin (doxorubicin) and P = CisPlatin. However, oncologists may also decide on additional treatments. These may include Ifosomide and Etoposide . . .

Decision Aid

The Osteosarcoma Decision Aid for Surgery in the Lower Limb is an online, interactive website designed to provide information about surgical options for newly diagnosed patients.


Clinical Trials

Currently, there is no standard of care for relapsed/refractory osteosarcoma. There are numerous ways to think about treating relapsed/refractory osteosarcoma, and a clinical trial is one of the options. This post discusses how to think about choosing a clinical trial. . .

Count Me In

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute, and Count Me In, a non-profit research initiative that conducts . . .


Following is a compilation of research into osteosarcoma, both Theresa Beech’s ¹ and other peoples, as well as some speculative thoughts. The bottom-line answer to both . . .

About Osteosarcoma

Osteosarcoma is a rare form of cancer (approximately 20,000 cases per year). It’s rarity makes it less studied and less understood than other forms of cancer.

Genetic Testing

Germline Testing

When a child is diagnosed with osteosarcoma very young (typically below the age of 10) or has a strong family history of sarcomas/breast cancer/GBM, or when a patient relapses, genetic testing may be mentioned…

Tumor Testing

In many adult cancers, at diagnosis, a biopsy of the tumor is done and some of the tumor tissue is sent off for genetic testing. Then, depending on the results of the genetic testing, a particular treatment is chosen…